I watched an amazing video this week by Mark Russinovich on how to use SysInternals while malware hunting. I strongly encourage everyone to check it out. It is long (86 minutes) but I wish he had gone longer. It is just full if useful information.
Video Here: http://channel9.msdn.com/Events/TechEd/NorthAmerica/2012/SIA302
Great video, thanks for posting!